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Ethics declarations Ethics approval and consent to participate This study was approved by Ethics Committee II of the Medical Faculty Mannheim at the University of Heidelberg, Germany (Ethics approval number: 2018625 N) and is in accordance with the requirements of the World Medical Associations Declaration of Helsinki

THC, or tetrahydrocannabinol, is the cannabinoid responsible for the psychoactive effects of cannabis

All accepted PMTAs proceed through filing review, which ensures the application contains all the items required under Section 910(b)(1), including, but not limited to, full reports of all information concerning investigations which have been made to show the health risks of the tobacco product and whether the tobacco product presents less risk than others

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S2CID 38714379